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Our Latest Updates
Birmingham BBQ Legends Rodney Scott and Nick Pihakis to Judge CahabaQue BBQ Cook-Off on April 15
Big win for breast cancer research! Over $115,000 raised at 14th annual Pink Palace Casino Night
4 Things to Know About Pink Palace Casino Night: Q&A with Megan Carter
CURRENT RESEARCH
What We're Funding
Thanks to generous supporters like you, the BCRFA invested $1.275 million in 24 breast cancer research projects at 7 institutes across the state in 2022.
Birmingham
Evaluating associations of rurality and neighborhood disadvantage with racial disparities in breast cancer mortality among women in the state of Alabama
Ritu Aneja, PhD
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Predicting the Risk of Heart Failure in Breast Cancer Survivors
Smita Bhatia, MD, MPH
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Cellular and Molecular Basis of the Neurological Effects of Chemotherapy
James Bibb, PhD and Etty (Tika) Benveniste, PhD
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FAM129B/NIBAN2 as a biomarker for therapy with NRF2 inhibitors
Anindya Dutta, MD, PhD
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Targeting CSF1R/PU.1 signaling and PU.1 super-enhancer regulation in tumor progression across breast cancer subtypes
Blake Eason Hildreth, III, DVM, MS, PhD
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Phase II single arm trial of low dose capecitabine in patients with advanced breast cancer
Katia Khoury, MD
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Hijacking axonogenesis to promote breast cancer by a subset of regulatory T cells
Jianmei Leavenworth, MD, PhD
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Research Support for Breast Surgical Fellow
Catherine Parker, MD
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Elucidating the effects of hypoxia on ribosome biogenesis in breast cancer
Dr. Amr Rafat
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Unique Arteriolar Niche in Expansion of Breast Cancer Stem Cells for Metastasis
Bin Ren, MD, PhD
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Identification of HIF-1a interactors in the nucleolus of breast cancer cells
Rajeev Samant, PhD
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A novel clinically actionable approach to disable resurgence and metastasis of triple-negative breast cancer
Lalita Shevde-Samant, PhD
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Intercellular Mitochondrial Trafficking as a Novel Mechanism in Breast Cancer Progression and Metastasis
Keshav Singh, PhD
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Developing novel AKT degrader to selectively inhibit the growth of PI3K/AKT/PTEN pathway mutant breast cancer
Jia Xu, PhD
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RNF2 ablation stimulates durable NK-CD4+ T cell-dependent anti-tumor immunity
Eddy Yang, MD, PhD and Zhuo Zhang, MD, PhD
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Chronic stress-regulated tumor-neuroimmune network in triple-negative breast cancer
Chao Zhang, MD, PhD
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Getting the right treatment to the right patient by matching regimens to patient biopsy before treatment
Karim I. Budhwani, PhD, DLA and Chelsea Crawford, PhD
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Mobile
WNK1, A Novel Regulator of Metastatic Breast Cancer
Dr. Debanjan Chakroborty
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Contribution of PERK+ Polyploid Giant Cancer Cells in the Ethnic Disparity of Triple Negative Breast Cancer
Dr. Luis del Pozo-Yauner
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Influence of stress on immune landscape and spatial heterogeneity of breast cancer
Dr. Seema Singh
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Auburn
Highly Active Liposomal Formulation of Proteasome Inhibitor Carfilzomib for the Treatment of TNBC
Dr. Alexei F. Kisselev
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Tuskegee
Cancer genomic study to characterize genetic and epigenetic diversity of immune landscape in triple negative breast cancer in women of African ethnicity
Dr. Deepa Bedi
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Huntsville
Inherited Breast Cancer Risk Screening and Education – Historically Black Colleges and Universities Expansion
Dr. Sara Cooper
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Tuscaloosa
Carrier-free Quercetin Nanoparticles for Overcoming Breast Cancer Drug Resistance
Dr. Yuping Bao (University of Alabama) and Robert D. Arnold (Auburn University)
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BREAKTHROUGHS IN RESEARCH
See the BCRFA Impact
The BCRFA supports a comprehensive approach to battling breast cancer by investing in collaborative and innovative research to help diagnose, treat, prevent and eradicate the disease. Since its founding in 1996, the BCRFA has raised and invested nearly $14 million dollars in research, helping our partners across the state receive sought-after and sustaining grant dollars from national funders, as well as develop new programs.
$11.5 Million Dollar Grant Pilot funding that led to the receipt and renewal of the Breast Cancer SPORE Grant
Collaborative Research
In 2016, the BCRFA launched a new award funding innovative collaborative partnerships in the field of breast cancer. This two-year $50,000 annual grant is awarded annually to primary investigators conducting collaborative research at the O’Neal Comprehensive Cancer Center at UAB and other research institutes in the state of Alabama, focusing on breast cancer research.
Personalized Medicine
$6.4 Million Dollar Grant Pre-clinical Lab Testing
Microarray Facility
The O’Neal-Sokol Breast Cancer Research Foundation of Alabama Endowed Chair
Breast Cancer Survivorship Clinic
BCRFA “Seed Money”
Funding provided by the BCRFA can have a multiplier effect of up to $16 for each dollar received by the UAB Cancer Center.
Imaging Facility
Helped fund the In Vivo Imaging facility which supports the Three Distinct Research Studies in breast cancer
World-Class Scientists
Funds to recruit and retain world-class breast cancer researchers at the UAB Comprehensive Cancer Center
BCRFA Endowed Professorship
Through the establishment of the BCRFA Endowed Professorship, the BCRFA will support UAB in their efforts to:
Recruit the best talent and faculty in the area of breast health and cancer treatment come to Alabama; Advance breast cancer patient outcomes; Impart knowledge to future generations of medical professionals, scientists, and researchers; Facilitate research which could translate to new therapies for other types of cancer.
BLOG
Read Stories from Real People Impacted by Breast Cancer
25 for Research: Roy Waite
25 For Research: Kay Zarzour
25 For Research: Phil Passafiume
